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hWmo8+jE'"m{F This equates to a weight loss of 10-20 pounds for a 200 pound . 104 0 obj <> endobj %%EOF Below is a chart of body mass index (BMI) based on various heights and weights. Also available as phentermine hydrochloride; dosage expressed in terms of phentermine hydrochloride. Phentermine is not to be used while pregnant or breastfeeding under any circumstances. Phentermine Hydrochloride Tablets, USP 37.5 mg are white oval shaped bisected tablet with blue specs, debossed with 810 on bisected side. Burguera B, et al. They inhibit the activity of an entire enzyme family known as monoamine oxidase. 99-8; s. 2, ch. In some cases, the use of Phentermine has also led to the development of symptoms that are related to erectile dysfunction. Phentermine is a schedule IV drug that requires a consultation with the doctor and a prescription. Obesity has been linked to many different diseases, including type 2 diabetes and cardiovascular disease. It is often prescribed to be taken in the morning, before or after breakfast. To provide you with the most relevant and helpful information, and understand which Pursuant to Board of Medical Examiners Rule 540-X-4-.05, dispensing physicians are required to register with the Board. The written prescription must be dated and signed by the prescribing practitioner on the day when issued. In relatively short-term clinical trials, adult obese subjects instructed in dietary management and treated with anorectic drugs lost more weight on the average than those treated with placebo and diet. If the time is too close to the next dose, it is recommended to skip the dose they have missed. 121 0 obj <>/Filter/FlateDecode/ID[<5D80FCFEE48BF540827EEA7155FB4128>]/Index[104 35]/Info 103 0 R/Length 85/Prev 180155/Root 105 0 R/Size 139/Type/XRef/W[1 2 1]>>stream If you take too much of this medicine, it may become habit-forming (causing mental or physical dependence). Data sources include IBM Watson Micromedex (updated 2 Apr 2023), Cerner Multum (updated 17 Apr 2023), ASHP (updated 10 Apr 2023) and others. Drugs to treat obesity; rules establishing guidelines. Javascript must be enabled for site search. Both the law and the rule for treating obesity outline practice guidelines for the safe use of phentermine, fenfluramine, and ot her drugs used to . Skip to Navigation | Skip to Main Content | Skip to Site Map. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Patients must be informed that Phentermine hydrochloride is a short-term (a few weeks) adjunct in a regimen of weight reduction based on exercise, behavioral modification and caloric restriction in the management of exogenous obesity, and that coadministration of Phentermine with other drugs for weight loss is not recommended [see Indications and Usage (1) and Warnings and Precautions (5.1)]. There is a problem with Ask your healthcare professional how you should dispose of any medicine you do not use. This content does not have an Arabic version. Numerous side effects have been linked to the use of Phentermine. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). The drug is classified under a certain chemical class known as amphetamine as it has a similar pharmacology value to other drugs classified in the class. Taking Phentermine depends on the brand and preparation of the drug. %PDF-1.4 % Primary Pulmonary Hypertension (PPH) a rare, frequently fatal disease of the lungs has been reported to occur in patients receiving a combination of Phentermine with fenfluramine or dexfenfluramine. This medication has been linked to physical dependence, which means a patient may become addicted to it. endstream endobj 108 0 obj <>stream If the prescription is for an animal, the species of animal for which the controlled substance is prescribed. History-New 12-4-97, Amended 2-17-98, 8-8-22. Mayo Clinic does not endorse companies or products. Skip to Navigation | Skip to Main Content | Skip to Site Map. It also isn't for people who are pregnant, may become pregnant or are breastfeeding. The dosage varies from 15mg to 37.5mg per day. This search engine indexes the Drug Enforcement Administration Diversion Control Program Web Site (www.deadiversion.usdoj.gov) only. SE, which stands for Electronic Florida Online Reporting of Controlled Sub-stances Evaluation program. Mayo Clinic does not endorse companies or products. Drugs of this class used in obesity are commonly known as anorectics or anorexigenics. It has not been established that the primary action of such drugs in treating obesity is one of appetite suppression since other central nervous system actions, or metabolic effects, may also be involved. In fact, one study conducted at the Duke University School of Medicine found that apart from the Phentermines ability to effectively reduce body weight, it can also help improve a patients health-related quality of life. Apart from not combining Phentermine with the MAO inhibitors, a patient should also first ensure they are not allergic to Phentermine before they take it. Before starting with consumption of this medication, patients should get informed about potential adverse effects to be able to determine whether a newly-developed symptom is a sign of a health issue or just a side effect associated with Phentermine. If the prescriber is not available to verify a prescription, the pharmacist may dispense the controlled substance but may insist that the person to whom the controlled substance is dispensed provide valid photographic identification. If you are allergic to other stimulants, amphetamines, cold medications or diet pills, you have a higher risk of being allergic to these pills too. Experience with hemodialysis or peritoneal dialysis is inadequate to permit recommendations in this regard. information submitted for this request. The 2022 Florida Statutes (including 2022 Special Session A and 2023 Special Session B) 458.336 Drugs to treat obesity; rules establishing guidelines.. All rights reserved. i h,T h,T +h,T h,T 6B*CJ aJ mH nH ph u+h,T h,T B*CJ H*aJ mH nH ph u(h,T h,T B*CJ aJ mH nH ph u +h,T h,T 5B*CJ aJ mH nH ph u ~ P r 2 i $ hhhh hd 1$ 5$ 7$ 8$ 9D H$ `ha$gd,T $d 1$ 5$ 7$ 8$ 9D H$ a$gd,T " $ hhhh hd 1$ 5$ 7$ 8$ 9D @&H$ `ha$gd,T i gd,T $d x 1$ 5$ 7$ 8$ 9D H$ a$gd,T 2 1h:p,T / =!"#$% @ @ @ N o r m a l CJ _HaJ mH sH tH D A@ D D e f a u l t P a r a g r a p h F o n t R i R T a b l e N o r m a l 4 97-264. Any controlled substance listed in Schedule III or Schedule IV may be dispensed by a pharmacist upon an oral prescription if, before filling the prescription, the pharmacist reduces it to writing or records the prescription electronically if permitted by federal law. This is a label given to drugs that can be misused. Your email address will not be published. Of course, it is taken orally. You may opt-out of email communications at any time by clicking on https://www.uptodate.com/contents/search. The possible origins of the increased weight loss due to the various drug effects are not established. The name of the prescribing practitioner. %%EOF Phentermine may decrease the hypotensive effect of adrenergic neuron blocking drugs. The combined drug is approved for long-term use. The combined drug is approved for long-term use. Safety and effectiveness in pediatric patients have not been established. Phentermine hydrochloride/topiramate. This brand is manufacturedby Teva Pharmaceuticals (formerly GATE Pharmaceuticals). Therefore, coadministration of Phentermine and these drug products is not recommended. The goal of the drug is to help patients lose weight and increase energy since the withdrawal symptoms of include fatigue and weight gain through an increase in appetite, the product is rendered a waste of the patients time and money. 2012 Florida Statutes. Patients who have been on a Phentermine program should not suddenly stop using the drug. These lifestyle changes often include participating in regular exercise and physical activities, as well as eating a well-balanced diet that does not contain large amounts of calories or harmful substances. The dose of this medicine will be different for different patients. Children 16 years of age and youngerUse is not recommended. Of course, it is taken orally. Any pharmacist who dispenses by mail a controlled substance listed in Schedule II, Schedule III, or Schedule IV is exempt from the requirement to obtain suitable identification for the prescription dispensed by mail if the pharmacist has obtained the patients identification through the patients prescription benefit plan. The medication has been classified as a controlled substance in most countries and is also classified as a schedule IV prescription drug. If we combine this information with your protected The MAO inhibitors (Monoamine Oxidase Inhibitors) are used to treat depression, especially a specific type called atypical depression. There shall appear on the face of the prescription or written record thereof for the controlled substance the following information: The full name and address of the person for whom, or the owner of the animal for which, the controlled substance is dispensed. Adults and children 17 years of age and older. During the COVID-19 public health emergency (PHE), authorized providers can prescribe controlled substances via telehealth, without the need for an in-person medical evaluation. The number of such prescription, as recorded in the prescription files of the pharmacy in which it is filled. Overstimulation, restlessness, dizziness, insomnia, euphoria, dysphoria, tremor, headache, psychosis. Follow your doctor's dosing instructions very carefully. The pharmacist may dispense the controlled substance, in the exercise of her or his professional judgment, when the pharmacist or pharmacists agent has obtained satisfactory patient information from the patient or the patients agent. Do not double doses. When mental impairment is present while taking Phentermine, a patient is also advised not to drive to avoid the risk of being involved in an accident. information is beneficial, we may combine your email and website usage information with Some patients need to take the drug an hour before they eat breakfast, while others are advised to take it approximately one to two hours after breakfast. The risks include, but are not limited to: See also, for example, Adverse Reactions (6) and Use in SpecificPopulations (8). So some health care providers might order it for longer use. xb```f``ZAb 1av K3gI{$*i p400t UD J@X$Ybv k=:,fb[ a`x @ ! Primary Pulmonary Hypertension (PPH) a rare, frequently fatal disease of the lungs has been reported to occur in patients receiving a combination of Phentermine with fenfluramine or dexfenfluramine. 0000000596 00000 n Section 458.336, F.S. When tolerance to the anorectant effect develops, the recommended dose should not be exceeded in an attempt to increase the effect; rather, the drug should be discontinued. The doctor also looks at the patients medical history for any pre-existing medical conditions that the medication should not be taken with. The following adverse reactions are described, or described in greater detail, in other sections: The following adverse reactions to Phentermine have been identified: Primary pulmonary hypertension and/or regurgitant cardiac valvular disease, palpitation, tachycardia, elevation of blood pressure, ischemic events. This includes prescription and nonprescription (over-the-counter) medicines, dietary supplements, herbal remedies, or medicines for appetite control, asthma, colds, cough, hay fever, and sinus problems. Even after the period that the drug has been prescribed for, the doctor will often recommend to gradually stop using the Phentermine to avoid the withdrawal symptoms. We comply with the HONcode standard for trustworthy health information. It is a class IV controlled substance because of its serious side effects and addiction potential. 21 0 obj <> endobj other information we have about you. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. The safety and efficacy of combination therapy with Phentermine and any other drug products for weight loss including prescribed drugs, over-the-counter preparations, and herbal products, or serotonergic agents such as selective serotonin reuptake inhibitors (e.g., fluoxetine, sertraline, fluvoxamine, paroxetine), have not been established. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. History of cardiovascular disease (e.g., coronary artery disease, stroke, arrhythmias, congestive heart failure, uncontrolled hypertension), During or within 14 days following the administration of monoamine oxidase inhibitors, Known hypersensitivity, or idiosyncrasy to the sympathomimetic amines, Effect on the ability to engage in potentially hazardous tasks [see, Withdrawal effects following prolonged high dosage administration [see, Development of primary pulmonary hypertension [see, Development of serious valvular heart disease [see, Effects on the ability to engage in potentially hazardous tasks [see, The risk of an increase in blood pressure [see, the potential for developing tolerance and actions if they suspect development of tolerance [see, the risk of dependence and the potential consequences of abuse [see. Rule 4731-11-04 | Controlled substances for the treatment of obesity. The usual adult dose is one tablet (37.5 mg) daily, as prescribed by the physician, administered before breakfast or 1 to 2 hours after breakfast. However in the presence of topiramate, Phentermine Cmax and AUC increase 13% and 42%, respectively. Phentermine doctors network. This content does not have an Arabic version. Taking Phentermine depends on the brand and preparation of the drug. 21 15 2007-156; s. 5, ch. Long-term efficacy and safety of anti-obesity treatment: Where do we stand? A minimum weight gain, and no weight loss, is currently recommended for all pregnant women, including those who are already overweight or obese, due to obligatory weight gain that occurs in maternal tissues during pregnancy. . There is a problem with HVMs8WQl eLg*&{dd $_;lm |NggK6,M]gu\.BNB. Required fields are marked *. 188, ch. By: Susan St. John Pursuant to Section 456.44(3)(a), Florida Statutes, and Rule 64B-9.013(3)(a), Florida Administrative Code, a practitioner must evaluate a patient by taking a complete medical history and performing a physical examination prior to prescribing a controlled substance to a patient. The strength and dosage of Phentermine depend on the brand that is prescribed and the patients specific condition. The doctor may advise the patient to complete the remaining period of the program or help him/her end the program safely. 893.04 Pharmacist and practitioner.. 893.049(1)(d), (e),f.s. The effective date is January 1, 2020. Lomaira: One tablet three times a day, taken 30 minutes before meals.

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